• Área de Trabajo:

Biología de las infecciones, One Health, Programa de Investigación en Enfermedades Tropicales, PIET. 

• Grado Académico e institución donde se obtuvo:

PhD, Instituto Karolinska, Suecia

• Experiencia laboral:

Microbióloga Clínica y Catedrática

• Publicaciones referencias de los últimos 5 años:

-       Alvarez, L.P, Ruiz-Villalobos, N., Suárez-Esquivel, M., Thomson, N.R., Marcellino, R., Víquez-Ruiz, E., Robles, C.A, Guzmán-Verri, C. (2020). Molecular characterization of Brucella ovis in Argentina. Vet. Microbiol, 245 (December, 2019), 108703. https://doi.org/10.1016/j.vetmic.2020.108703

-       Suárez-Esquivel, M., Hernández-Mora, G., Ruiz-Villalobos, N., Barquero-Calvo, E., Chacón-Díaz, C., Ladner, J. T., Oviedo-Sánchez G., Foster, J.T., Rojas-Campos, N., Chaves-Olarte, E., Thomson N.R., Moreno, E., Guzmán-Verri, C. (2020). Persistence of Brucella abortus lineages revealed by genomic characterization and phylodynamic analysis. PLOS Neglected Tropical Diseases, 14(4), e0008235. https://doi.org/10.1371/journal.pntd.000823

-    Martínez-Brenes, A., Torres-Castro, K., Marín-Benavides, R., Acuña-Umaña, K., Espinoza-Araya, C., Ramírez-Carranza, R., González-Espinosa, G, Rojas-Campos N, Guzmán-Verri, C, Sáenz-Arce, G, Lesser-Rojas, L. (2019). Combined electrokinetic manipulations of pathogenic bacterial samples in low-cost fabricated dielectrophoretic devices. AIP Advances, 9(11), 115303. https://doi.org/10.1063/1.5049148

 -   Guzmán-Verri C, Suárez-Esquivel M, Ruíz-Villalobos N, Zygmunt MS, Gonnet M, Campos E, Víquez-Ruiz E, Chacón-Díaz C, Aragón-Aranda B, Conde-Álvarez R, Moriyón I, Blasco JM, Muñoz PM, Baker KS, Thomson NR, Cloeckaert A, Moreno E. Genetic and Phenotypic Characterization of the Etiological Agent of Canine Orchiepididymitis Smooth Brucella sp. BCCN84.3. Front Vet Sci. 2019 Jun 7;6:175. doi: 10.3389/fvets.2019.00175. eCollection 2019. Erratum in: Front Vet Sci. 2019 Aug 02;6:253.

-    Murillo T, Ramírez-Vargas G, Riedel T, Overmann J, Andersen JM, Guzmán-Verri C, Chaves-Olarte E, Rodríguez C. Two Groups of Cocirculating, Epidemic Clostridiodes difficile Strains Microdiversify through Different Mechanisms. Genome Biol Evol. 2018 Mar 1;10(3):982-998. doi: 10.1093/gbe/evy059.

-       Altamirano-Silva P, Meza-Torres J, Castillo-Zeledón A, Ruiz-Villalobos A, Zuñiga-Pereira AM, Chacón-Díaz C, Moreno E, Guzmán-Verri C, and Chaves-Olarte E. Brucella abortus senses the intracellular environment through the two-component system BvrR/BvrS allowing the adaptation to its replicative niche".  Infection & Immunity, 2018 Infect Immun 86:e00713-17. https://doi.org/10.1128/IAI.00713-17.

-       Villalobos-Vindas Juan M; Amuy E; Barquero-Calvo E; Rojas N; Chacon-Díaz C; Chaves-Olarte E; Guzmán-Verri C; Moreno E. Brucellosis caused by the wood rat pathogen Brucella neotomae: two case reports.

J Med Case Reports, 2017 11: 352. https://doi.org/10.1186/s13256-017-1496-8

-       Suárez-Esquivel M, Alfaro-Alarcón A, Guzmán-Verri C, Barquero-Calvo E. Analysis of the association between density of Helicobacter spp. and gastric lesions in dogs". Am J Vet Res., 2017 Dec; 78(12):1414-1420. doi: 10.2460/ajvr.78.12.1414.

-       Hernández-Mora, G, Ruiz-Villalobos N, Bonilla-Montoya R, Romero-Zúñiga JJ , Jiménez-Arias J, González Barrientos R, Barquero-Calvo E, Chacón-Díaz C, Rojas N, Chaves-Olarte E, Guzmán-Verri C, Moreno E. Epidemiology of bovine brucellosis in Costa Rica: lessons learned from failures in the control of the disease. PLOS ONE,  2017 Aug 10;12 (8):e0182380. doi: 10.1371/journal.pone.0182380.

-       Hernández-Mora, G, Bonilla-Montoya R, Barrantes-Granados O, Esquivel-Suárez A, Montero-Caballero D, González Barrientos R, Fallas-Monge Z, Palacios-Alfaro JD, Baldi M, Campos E, Chanto G, Barquero-Calvo E, Chacón-Díaz C, Chaves-Olarte E, Guzmán-Verri C, Romero-Zúñiga JJ, Moreno E. Brucellosis in mammals of Costa Rica: An epidemiological survey. PLOS ONE, 2017 09 Aug https://doi.org/10.1371/journal.pone.0182644

-       Suárez-Esquivel M, Baker KS, Ruiz-Villalobos N, Hernández-Mora G, Barquero-Calvo E, González-Barrientos R, Castillo-Zeledón, A, Jiménez-Rojas C, , Chacón-Díaz C, Cloeckaert A, Chaves-Olarte E, Thomson NR, Moreno E, Guzmán-Verri C. Brucella Genetic Variability in Wildlife Marine Mammals Populations Relates to Host Preference and Ocean Distribution. Genome Biology and Evolution, 2017 Jul 1;9(7):1901-1912. doi: 10.1093/gbe/evx137.

-       Araya-Hidalgo E, Gutiérrez-Jiménez C, Chaves-Ramírez M, Suárez-Esquivel M, Guzmán-Verri C, Barquero-Calvo E. Sequence analysis of the hypervariable region in hmtp210 of Avibacterium paragallinarum. J Vet Med Sci. 2017 Jul 19;79(7):1210-1214. doi: 10.1292/jvms.16-0530. Epub 2017 May 27

-       Suárez-Esquivel M, Ruiz-Villalobos N, Jiménez-Rojas C, Barquero-Calvo E, Chacón-Díaz C, Víquez-Ruiz E, Rojas-Campos N, Baker KS, Oviedo-Sánchez G, Amuy E, Chaves-Olarte E, Thomson NR, Moreno E, Guzmán-Verri C. Brucella neotomae infection in humans, Costa Rica. Emerg Infect Dis. 2017 Jun; 23(6):997-1000. doi: 10.3201/eid2306.162018

-       Campbell JI, Huong Lan NP, Phuong PM, Buu Chau L, Duc TP, Guzmán-Verri C, Ruiz-Villalobos N, Thi Minh TP, Muñoz Álvaro PM, Moreno E, Thwaites GE, Rabaa MA, Chau NVV, Baker S. Human Brucella melitensis infections in southern Vietnam. Clin Microbiol Infect. 2017 Jun 29. pii: S1198-743X(17)30352-X. doi: 10.1016/j.cmi.2017.06.028.

-       Baker KS, Campos J, Pichel M, Della Gaspera A, Duarte-Martínez F, Campos-Chacón E, Bolaños-Acuña HM, Guzmán-Verri C, Mather AE, Diaz Velasco S, Zamudio Rojas ML, Forbester JL, Connor TR, Keddy KH, Smith AM, López de Delgado EA, Angiolillo G, Cuaical N, Fernández J, Aguayo C, Morales Aguilar M, Valenzuela C, Morales Medrano AJ, Sirok A, Weiler Gustafson N, Diaz Guevara PL, Montaño LA, Perez E, Thomson NR. Whole genome sequencing of Shigella sonnei through PulseNet Latin America and Caribbean: advancing global surveillance of foodborne illnesses Clin Microbiol Infect. 2017 Apr 4. pii: S1198-743X(17)30190-8. doi: 10.1016/j.cmi.2017.03.021.                                                

-       Suárez-Esquivel M, Ruiz-Villalobos N, Castillo-Zeledón A, Jiménez-Rojas C, Roop Ii RM, Comerci DJ, Barquero-Calvo E, Chacón-Díaz C, Caswell CC, Baker KS, Chaves-Olarte E, Thomson NR, Moreno E, Letesson JJ, De Bolle X, Guzmán-Verri C. Brucella abortus Strain 2308 Wisconsin Genome: Importance of the Definition of Reference Strains.Front Microbiol. 2016 Sep 29;7:1557. doi: 10.3389/fmicb.2016.01557

-       Quesada-Gómez C, López-Ureña D, Chumbler N, Kroh HK, Castro-Peña C, Rodríguez C, Orozco-Aguilar J, González-Camacho S, Rucavado A, Guzmán-Verri C, Lawley TD, Lacy DB, Chaves-Olarte E. Analysis of TcdBs within the hypervirulent clade 2 reveals an impact of RhoA glucosylation in Clostridium difficile pro inflammatory activities. Infect Immun.  2016 March; 84 (3): 856-865. doi: 10.1128/IAI.01291-15                                                                         

-       Chacón-Díaz C, Altamirano-Silva P, González-Espinoza G, Medina MC, Alfaro-Alarcón A, Bouza-Mora L, Jiménez-Rojas C, Wong M, Barquero-Calvo E, Rojas N, Guzmán-Verri C, Moreno E, Chaves-Olarte E. Brucella canis is an intracellular pathogen inducing a lower proinflammatory response than smooth zoonotic counterparts. Infect Immun. 2015 Dec;83(12):4861-70. doi: 10.1128/IAI.00995-15.

-       Barquero-Calvo E, Mora-Cartín R, Arce-Gorvel V, de Diego JL, Chacón-Díaz C, Chaves-Olarte E, Guzmán-Verri C, Buret AG, Gorvel JP, Moreno E. Brucella abortus induces the premature death of human neutrophils through the action of its lipopolysaccharide. PLoS Pathogens. 2015 May 6;11(5):e1004853. doi: 10.1371/journal.ppat.1004853.

 -       Quesada-Gómez C, López-Ureña D, Acuña-Amador L, Villalobos-Zúñiga M, Du T, Freire R, Guzmán-Verri C, Gamboa-Coronado MD, Lawley TD, Moreno E, Mulvey MR, de Castro Brito GA, Rodríguez-Cavallini E, Rodríguez C, Chaves-Olarte E. Emergence of an outbreak-associated Clostridium difficile variant with increased virulence. J Clin Microbiol. 2015 Apr;53(4):1216-26. doi: 10.1128/JCM.03058-14. Epub 2015 Feb 4.